VP of Clinical Operations

VP of Clinical Operations Role:

Location:
Europe Based, Any

Department:
Clinical Operations

Type:
Hybrid

Position Summary:

The Vice President of Clinical Operations is responsible for the strategic oversight and operational execution of clinical trials across all phases (I–IV).
This role leads cross-functional teams to ensure the efficient, high-quality, and compliant delivery of clinical programs in alignment with corporate goals and regulatory requirements.
As a senior leader within the organisation, the VP of Clinical Operations plays a critical role in sponsor engagement, resource planning, and operational excellence.

Key Responsibilities:

- Lead and oversee all aspects of global clinical trial execution including planning, startup, enrolment, site management, data collection, and closeout.- Develop and implement clinical operations strategy to ensure successful delivery of clinical programs on time and within budget.- Manage and mentor clinical operations teams including Clinical Trial Managers (CTMs), Clinical Research Associates (CRAs), and support staff.- Serve as a key liaison with sponsors, investigators, regulatory bodies, and internal cross-functional teams (e.g.,
regulatory, data management, biostats).- Ensure trials are conducted in accordance with ICH-GCP, FDA/EMA regulations, and internal SOPs.- Collaborate with executive leadership to define timelines, budgets, risk mitigation plans, and resource allocation.- Drive continuous improvement initiatives related to clinical processes, vendor performance, quality control, and patient recruitment strategies.- Evaluate, select, and manage vendors such as CROs, central labs, and eClinical platforms.- Support regulatory submissions and inspection readiness activities.- Develop and track KPIs across the clinical portfolio to ensure operational excellence.

Qualifications:

~ Bachelor's degree in Life Sciences, Nursing, Pharmacy, or related field; Master’s or advanced degree (MS, MBA, MPH) preferred.

~Minimum 10 years of experience in clinical operations within a CRO, biotech, or pharmaceutical company.

~ At least 5 years in a senior leadership role with direct oversight of clinical trial execution and team leadership.

~ Strong working knowledge of ICH-GCP, FDA, EMA, and other international clinical trial regulations.

~ Proven success in leading multi-centre, global clinical studies from startup to closeout.

~ Experience managing large teams and clinical budgets.

~ Excellent organizational, communication, and strategic thinking skills.

~ Demonstrated ability to manage multiple projects and shifting priorities in a fast-paced environment.

Preferred Experience:

• Experience with electronic clinical systems (eTMF, EDC, CTMS, eCOA, IRT, etc.).
• Familiarity with oncology, rare disease, CNS, or other complex therapeutic areas.
• Prior involvement in regulatory submissions (IND, NDA, BLA) is a plus.
• Experience working with decentralized/hybrid trial models is desirable

Compensation & Benefits:

> Competitive executive compensation with performance-based incentives

> Health, dental, vision, and life insurance

> Equity or stock option opportunities (for biotech/pharma)

> Competitive salary

> Generous PTO and flexible work environment

> Professional development and leadership training support

This opportunity has been incredibly popular.
We encourage all candidates to apply immediately, as it is likely that recruitment may close prematurely.